geNetClassifier classify multiple diseases and build associated gene networks using gene expression profiles

نویسندگان

  • Sara Aibar
  • Celia Fontanillo
  • Conrad Droste
  • Javier De Las Rivas
چکیده

3 Main function of the package: geNetClassifier() 5 3.1 Loading the package and data . . . . . . . . . . . . . . . . . . . . . . . . 6 3.2 Run geNetClassifier() . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3.3 Overview of the data returned by geNetClassifier() . . . . . . . . . . . . 9 3.4 Return I: Genes ranking . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 3.4.1 Significant genes . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.5 Return II: Classifier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 3.5.1 Gene selection procedure . . . . . . . . . . . . . . . . . . . . . . . 16 3.5.2 Estimation of performance and generalization error procedure . . 18 3.6 Return III: Gene networks . . . . . . . . . . . . . . . . . . . . . . . . . . 21

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تاریخ انتشار 2013